Tyrese Samuel scored a career-high 28 points, Zyon Pullin added 21 and Florida never trailed in an 83-74 victory over Missouri on Wednesday night.
The Gators (20-8, 10-5 Southeastern Conference) won for the ninth time in 11 games to reach 20 victories for the first time since the 2017-18 season. The Tigers (8-20, 0-15) lost their 15th in a row and guaranteed a last-place finish in the league as well as the 14th seed in the conference tournament.
Sean East II led the Tigers with 20 points.
Missouri hosts Mississippi on Saturday.